Current projects

We are current working on the following initiatives to optimise quality of prescribing and support reduction of antimicrobial resistance aligned with the ambitions of the Chief Medical Officer's Realistic Medicine approach.

Penicillin allergy de-labelling

About 10% of the population are labelled as ‘penicillin allergic’, yet of this number around 90% of patients are not truly allergic and many could safely receive penicillin antibiotics. We are working with clinical teams to develop and test a risk algorithm to support assessment of penicillin allergy in patients whose history suggests that previous reaction to penicillin was not allergic in nature so that their allergy label can be removed. This is important as penicillin antibiotics are the best treatment for many types of infection, and alternatives may have more side effects and be less effective.

Towards the end of life antibiotics

This new initiative brings together clinicians from across hospital and community settings to develop good practice recommendations on when and when not to use antibiotics in patients during their last days and weeks of life. This is important to ensure the best use of antibiotics in patients who are dying and prevent any harmful antibiotic-associated side effects and complications which may impact on quality of life in a person’s final days.